Neal Rouzier, MD on Hormones & Beyond 2020
Four years ago we started the first WLM Conference entitled Beyond Hormones Part 5. The theme of the first course was The Gut. Specialists presented various diagnostic approaches for GI work-up beyond conventional tests as well as various treatments to improve gut health, most of which is never taught in our residencies. The following year focused on the brain. I presented many papers demonstrating how hormones can improve brain function and protect against Alzheimer’s disease and dementia. Dr. Ken Sharlin reviewed his functional medicine approach and all of Bredesen’s protocols. Last year I focused on cardiovascular disease and diabetes. Jason Fung presented all his data and research on intermittent fasting. The amount of studies and data and the outcome studies for reversing diabetes and CVD was unsurpassed. I still have high hopes of taking that course to a national level which will far surpass any Cardio-Metabolic Summit where they just don’t grasp anything beyond more drugs that don’t work and fail to address the source of the problem.
After each Beyond Hormones course, I wrack my brain trying to figure out what to do for the following year as far as a theme goes. What organ or system should we focus on that is of utmost importance and is not addressed well by mainstream medicine? Rather, what disease entity should we address that, similar to hormones, mainstream medicine doesn’t address well and remains oblivious to despite a plethora of data? Although I touch on the topic in Part 2, I would like to provide all the latest and greatest literature review of the topic that is of such great importance from a morbidity and mortality perspective but for which mainstream medicine still provides no significant prevention-and that is cancer.
Each day that I spend hours reading and researching various cancer topics, I am amazed at the literature and data that addresses various modalities and treatments to protect against cancer. I do not find that any medical specialty that addresses and focuses on these issues and the one specialty that you would expect to be on the front line of defense is the one that knows the least about cancer prevention-the oncologists. Sadly, most oncologists know little about prevention and their main armamentarium are chemotherapeutic agents. Similar to CVD and DM, practitioners treat the disease once diagnosed but no one focuses on prevention. I will. Finally, what does one do after treatment of cancer? Since hormones are verboten in cancer survivors, just what is one to do other than letting patients suffer? Again, we must resort to medical science and literature to support what we do. I will extensively review all the recent data on prevention and treatment of the common cancers we encounter. Oh, and I almost forgot. What specialist is the best at preventing cancer? You are.
Unfortunately, I’m frequently called upon to defend clinicians that get sued for various circumstances involving cancer. Fortunately, I love to defend these cases as 1) knowledge is power and knowing and having access to all the medical literature provides confidence and power in treating patients, 2) oncologists and specialists are oblivious to their own medical literature which makes them lose credibility, 3) specialists testify just on their opinions which I refute with medical literature, 4) specialists can’t refute what I present because it is their own literature. So, for education sake, for your confidence and credibility, and entertainment from my play-by-play of several cases, I will present several cancer cases that we should all be aware that can happen and how to properly document and provide chart literature for every patient we treat. This section starts off scary but in the end you will be elated that I took you through the process. Trust me, all have good endings.
Last year Dr. Fung introduced AMP-K pathway and mentioned that metformin might be the magic potion for augmenting this pathway. So we will look at this pathway and dissect it, find out where it is good and bad, and how to optimize it with drugs, hormones, and supplements. I personally view metabolic aberrations, mitochondrial dysfunction, inflammation, autophagy, DM, CVD, NAFLD, and cancer as being part of the same, complex disease process. We’ll dissect this disease process and see how we can reverse the intracellular gene promoters and suppressors.
I still view posts that make claim that estrogen is responsible for breast cancer. A recent article in JAMA called for universal use of SERMs and AIs to prevent breast cancer. So we will review the mechanism of breast cancer development and how to prevent it. We’ll also look at the harmful effects of the various medicines prescribed to breast cancer survivors. There are medicines that work much better than drugs. (Hint: hormones are medicines). Ever wonder why every study proves that higher levels of estradiol are associated with a higher risk of breast cancer? Ever wonder why every study proves that estrogen administration protects against breast cancer? What are the mechanisms involved here? And what should we do with women with a positive family history or BRCA gene defects? We’ll review all gynecologic cancers, treatments, and outcomes that we should be aware of.
Lastly, prostate cancer has undergone tremendous fluctuation in treatments from androgen ablation to supraphysiolgic treatment with testosterone. That’s akin to pouring gas on a fire to put it out. Recent studies demonstrate what the mechanism is for testosterone being protective against prostate cancer development. So what should we do for men with strong positive family history and + BRCA gene defect? Remember that this process is a compendium of disease, from early spectrum to latent cancer formation. We’ll review all the recent literature on prostate cancer. Dr. Clifford Gluck is a foremost expert on HIFU and he will present the latest research in diagnosing and treating prostate cancer with an alternative approach.
What would a WLM conference be without a HRT update? Yep, there’s tons of new stuff that I’ll try to cram into a 2 hour update. I’ll spend another hour utilizing the medical literature to demonstrate why I take 50 mg of melatonin nightly for cancer prevention as well as a host of other benefits. Yep, it’s better than metformin and I’ll prove it to you. Melatonin should be the anti-aging drug and not metformin.
After my residency in Emergency Medicine, I went on to do a fellowship in toxicology. Now realizing that everything in the environment is polluted and toxic, I don’t want to go outside or even breathe. But life goes on and we just have to be as careful and cautious as one can be. However, what does one do to counteract endocrine disruptors? What are they, what do they do, how should we counter them and what should we know about them? All day Saturday will be lectures on the various aspects of endocrine disruptors, xeno-estrogens, environmental toxins, and the various methods of detoxing from the world in which we live. Our featured guest speaker for this topic is Anthony G Jay, Ph.D. author of the Estrogeneration.
I keep my faith intact, make sure my prayers are said, cause I’ve learned that the Monsters ain’t the ones beneath the bed. – Eric Church
We look forward to seeing you all in person and hope this is a time where that can all happen. Till then we are all working hard to put together another outstanding program.
Neal Rouzier, MD